Chunk #2 — Methods and Materials — Subject Recruitment — Initial Discovery Sample: Center for Education and Drug Abuse Research and Substance Abuse and the Dopamine System
Probands in the Substance Abuse and Dopamine System (SADS) study were male subjects 12 to 18 years of age, having a DSM-IV diagnosis of substance dependence related to use of illicit drugs. Probands were recruited from substance abuse treatment programs. The CEDAR and SADS subjects were self-identified European-Americans from the same Greater Pittsburgh geographic area, and the genomic inflation factor based on all genotyped SNPs, evaluating the excess false-positive rate, was satisfactory at .98.
