Based on the GWAS results from EAs, we TaqMan genotyped four SNPs in another 3112 subjects recruited using the same methodology for follow-up. These four SNPs were also genotyped in 5504 of the 5799 GWAS subjects for estimating genotyping error rates. Two of the four SNPs, rs406001 and rs450378, were located on chromosome 7p12. The linkage disequilibrium (R2) between them was .54. The other two SNPs, rs6812849 and rs7691872, were located in the first intron of TLL1. They were in high linkage disequilibrium (R2 = .88). By comparing the genotyping results from TaqMan and the GWAS array, the measured discordance rates for rs406001, rs450378, rs6812849, and rs7691872 were .20%, .65%, .71%, and .29%, respectively.
