Table 1 presents the individual GWAS results for the 6 indicators in the multivariate GWAS. Our final model for EUR-like veterans (Neff = 310,498) contained all six indicators and showed reasonably good fit to this model specification (Figure 1, Panel A; χ2= 104.10, df = 7, p = 1.53x10−19; CFI = 0.99, SRMR = 0.06). For the AFR-like veterans, the genetic correlation between SMOK and TUD was indistinguishable from one. We therefore retained only TUD, as it had greater statistical power. We also replaced ADHD with the attention problems subscale of the Medical Outcomes Survey as a proxy (MOS-ATTN, h2SNP [SE] = 0.033 [0.009], LDSC intercept = 1.003, Mean χ2 = 1.038, λGC = 1.035, rG with ADHD = 0.8) due to the low power of the ADHD indicator. The final model for AFR-like veterans (Neff = 99,949) therefore, largely mirrored that of the EUR-like veterans with one fewer indicator (Figure 1, Panel B; χ2 = 131.51, df = 8, p = 1.38x10−24; CFI = 0.96, SRMR = 0.09).
