Brain activation in resting state is highly similar to the functional activity in a cognitive task. It is increasingly believed that intrinsic activations shape patterns of cognitive task activations and predict cognitive ability (Smith et al., 2009; Cole et al., 2016; Schultz and Cole, 2016). Thus, resting state fMRI is a promising tool to explore intrinsic brain activity and its relationship with cognitive processes, with extensive use of regional homogeneity (ReHo) and functional connectivity (FC) analyses. ReHo supposes that voxels within a functional brain area are more temporally synchronous when this area is involved in a specific condition (Zang et al., 2004). It is applied in the prediction of variations in cognitive performance in healthy people by detecting regional signal changes (Tian et al., 2012). In addition, significant abnormalities in spontaneous low-frequency fluctuations coherence have been observed in patients with AD. ReHo has been speculated to be a biomarker of disease progression in patients with AD and MCI (He et al., 2007; Zhang et al., 2012). FC evaluates the interregional connectivity between spatially remote brain regions. Functional interactions between distinct
