alcohol consumption and matched controls, ADH1B*2 was associated with protection from heavy drinking in both men (OR = 0.19, p = 4.8×10−10) and women (OR = 0.48 p = 0.0067); other ADH SNPs were not significant when conditioned upon rs1229984 (Munoz et al., 2012). Interestingly, rs12299842 was recently associated with attendance at a pub or social club in Great Britain (p = 4.2 × 10−25) (Day et al., 2018).
