cells (CA1) was confirmed in SCZ, cognitive performance, intelligence, cross-disorders, and overall sleep duration. Additionally, pyramidal cells (CA1) were enriched in cigarettes smoked per day. However, the strongest consistent evidence was found for enrichment of GABAergic neurons from the prefrontal cortex and midbrain in various psychiatric disorders, SUDs, and behavioral/quantitative phenotypes. Consistent with findings using 10x Genomics and KI data, fewer enriched cell types were identified in neurological disorders. Human microglia were enriched in Alzheimer’s disease and human inhibitory GABAergic neurons from the prefrontal cortex and midbrain in generalized epilepsy. Generalized epilepsy was the only neurological phenotype in which mouse cell types were identified, namely certain pyramidal neurons and certain inhibitory neurons. We thus largely confirmed the main cell type enrichment findings from the 10x Genomics and KI dataset in mouse datasets and in human datasets using FUMA.
