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Chunk #3 — METHODS — Selection of independent signals

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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
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Given the genome-wide results of the meta-analysis, SNPs showing evidence for association at genome-wide significant P-values were selected and clumped based on a physical (kb) threshold <1 Mb. The lead SNPs of the 105 clumps formed constitute the list of SNPs independently associated with age at menarche (Extended Data Tables 1-4).