samples and meta-analysis) are shown in Supplement Figures 2–4. Individual-sample level Manhattan and QQ plots for AD-CrC are shown in Supplemental Figure 5. (Rs671 was directly genotyped in both samples. Rs143894582 was imputed in both samples, with imputation score 0.801 in sample 1 and 0.872 in sample 2; rs149212747 was also imputed in both samples, with imputation score 0.900 in sample 1 and 0.968 in sample 2.)