To link GWS SNPs to relevant protein coding genes, we applied three gene mapping approaches implemented in FUMA: positional mapping, expression quantitative trait loci (eQTL), and chromatin interaction mapping (Supplementary Table 9). GWS SNPs within the 81 EA loci mapped to 415 protein coding genes under at least one mapping strategy. A total of 230 genes (55%) were mapped by two or more strategies, and 85 (20%) genes were mapped by all three strategies (Supplementary Fig. 6). Notably, some genes were implicated across independent risk loci by chromatin interactions/eQTL mapping, including EFNA5, GRIA1, FOXP2, MDFIC, WSB2, VSIG10, PEBP1, and C17orf58. Chromatin interaction plots are shown in Supplementary Data 3.
