Supplemental Table S2 presents gene-based association test results for previously identified addiction candidate genes (Hodgkinson et al. 2008), none of which were significant after adjustment for multiple testing (minimum p=1.4×10−3). Supplemental Table S3 gives results for each of the addiction candidate gene sets tested in CADD. None of the addiction candidate gene sets showed evidence of greater-than-chance overlap with low p-value genomic regions in the CADD GWAS (minimum p=5.0×10−1).
