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Chunk #50 — Online Methods — Genome-wide survival association study datasets — (4) Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE)

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A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.
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a covariate in FHS analyses. After exclusion of prevalent dementia, dementia other than AD, and missing values, a sample of 2,208 participants was available for this project. The FHS component of this study was approved by the Institutional Review Board of the Boston Medical Center.