We assessed the impact of variation at rs11174811 on brain expression levels of AVPR1A. A sample of 91 postmortem brain samples (dorsolateral prefrontal cortex) from the Stanley Medical Research Institute was used to conduct quantitative real-time polymerase chain reaction to test the functional significance of the genetic findings. The association was tested by t test and linear regression to account for important covariates (pH, postmortem interval, sex, diagnosis).
