Table 1 presents the top 50 results for the single SNP analyses in male and female subjects combined, as well as the results of allelic tests performed separately by gender. The genotypic odds ratios and accompanying p values derive from the Cochran-Mantel-Haenszel tests stratified by gender. In each of the 50 SNPs, the Breslow-Day tests indicate no heterogeneity. The allelic odds ratios are obtained in Pearson 1 − df χ2 allelic association tests on the data arranged in 2 × 2 contingency tables. Throughout, we present p values that are not corrected for multiple comparisons. If we were to treat each gene as an independent hypothesis test, we would set a Bonferroni experiment-wide corrected p value for gene-wise tests at a threshold of ∼4.7 × 10−4 after controlling for 106 genes.
