We identified 25 traits with immune enrichment at FDR<5% in our gene expression and/or chromatin analyses (Online Methods). We investigated cell-type-specific enrichments for these traits using gene expression data from the ImmGen project21, which contains microarray data on in 292 immune cell types from mice (Online Methods). This data set contains data for many immune cell types that are not available in the multiple-tissue analysis, and because we compute t-statistics within the data set—i.e., each immune cell vs. other immune cells—the gene sets are less overlapping than those of immune cell types in the multiple-tissue analysis.
