Most eQTS associations (72.8%) represented blood-cell traits (Extended Data Figure 3, Supplementary Data 5). For instance, the PGS for mean corpuscular volume40 correlated positively with the expression of genes specifically expressed in erythrocytes, e.g. genes encoding hemoglobin subunits (HBG1 and HBG2, both FDR<0.05). eQTS genes were most enriched by GO terms involved in cellular secretion, blood cell traits and intercellular signaling (Supplementary Table 14).
