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Chunk #31 — Results

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Alcohol use disorder is associated with altered frontomedial phase-amplitude coupling strength during resting state.
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This pattern of broadly greater PAC strength in AUD groups appears to diverge by sex in the theta-gamma and delta-gamma domains (Fig. 2, Fig. 3A). While candidate clusters in the theta-gamma domain indicated greater PAC in the AUD groups of both men (Fig. 2A, cluster 10) and women (Fig. 3A, clusters 11, 12), only the M10 cluster rose to significance (AUD median = 0.7572, unaffected median = 0.7467, U = 23386, p = 0.0187, CLES = 0.567, r = 0.135).