2004; Rolls et al., 1994). Cases of frontotemporal dementia with OFC pathology are also marked by compulsive consummatory behaviors, including hyperphagia, gambling, and substance abuse (Gorno-Tempini et al., 2004; Ikeda et al., 2002; Rosen et al., 2005; Thompson et al., 2003; Whitwell et al., 2007; Williams et al., 2005; Woolley et al., 2007). Thus, the pattern of behavior seen with OFC damage in humans, as well as in non-human primates and rodents (Bechara, 2005; Schoenbaum et al., 2006), is highly reminiscent of addictive behavior.
