The mediation analysis suggested a negligible direct association between sensation seeking and AUD (β g = 0.02, SE = 0.02, P = .324) after accounting for an alcohol consumption‐mediated pathway (Figure 1B; Table S16). The significance of the indirect path, calculated using the Sobel test 55 (β g = 0.17, SE = 0.01, P = 2.73 × 10−39), suggested full mediation.
