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Chunk #48 — Review

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Genome-wide association studies in ADHD.
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meta-analysis (Lewis et al. 2003)Also lies within suggestive linkage region for ADHD reported in the same publication (Lesch et al. 2008)rs2199161111.62E-065q13.271446112In intron of MAP1B Encodes microtubule-associated protein 1B, a member of a protein family thought to be involved in microtubule assembly, which is an essential step in neurogenesis. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. Finding lies within linkage region for ADHD from meta-analysis (Zhou et al. 2008c)Also lies within suggestive linkage region for ADHD reported in the same publication (Lesch et al. 2008)rs16928529123.90E-0610q22.172652991In intron of UNC5B Encodes unc-5 homolog B (C. elegans), which belongs to a family of netrin-1 receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. Finding lies in linkage region for bipolar disorder (1997)rs2677744139.69E-0715q26.189251445In intron of MAN2A2 Encodes mannosidase, alpha, class 2A, member 2, expressed in brain and many other tissues. The protein is involved in N-glycan synthesis. The finding lies close to linkage regions for autism (Szatmari et al. 2007b) and major depressive disorder (Holmans et al. 2007)rs7175404146.03E-0715q26.191837692In intron of AK094352 Gene of unknown function. The finding lies close to linkage region for major depressive disorder (Holmans