Childhood adversity showed a significant association with AUD severity (Table 1). The adjusted mean AUD severity (number of criteria) was 0.71 greater in those who experienced childhood adversity compared to those who did not. In addition, ADH1B-rs1229984 was significantly associated with AUD severity (Table 1). The adjusted mean AUD severity was 0.27 greater in the GG group than in the AA/AG group.