From the three studies above, a total of 2,257 individuals were selected for these association studies. Participants were first chosen based on whether an adequate genomic DNA sample was available. Then, participants were ordered using a diagnostic hierarchy (highest to lowest), regardless of whether they were probands or affected relatives: restricting AN (RAN), AN with purging but no binging (PAN), AN with binge eating with or without purging (BAN), a lifetime history of both AN and BN (ANBN), subthreshold AN with no binging or purging, purging BN, non-purging BN, and subthreshold BN. The individual from each family with the diagnosis that was highest on the hierarchy was selected. These participants as well as 677 control women from the AN Trios Study were defined as the primary samples for inclusion. A secondary set of samples was selected based on the criteria above and each of these participants was related to one individual in the primary sample. Genomic DNA samples from these individuals were sent to Illumina for genotyping. Of these individuals, we removed 11 participants whose DNA samples failed genotyping; 220
