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Chunk #14 — METHODS — Using SPOT

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SPOT: a web-based tool for using biological databases to prioritize SNPs after a genome-wide association study.
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The main page consists of a web form for the primary user input. Users must first either upload a list of numeric SNP identification numbers as a file or enter the list directly into a web form. The user may optionally provide P-values from statistical tests for genotype–phenotype correlation. In the section labeled ‘Prioritization of specific genes and other genomic regions’, the user can specify a list of genes and prioritization scores to be used in the ‘User Gene’ node of the GIN model.