A two-way analysis of variance (ANOVA) was used to analyze errors (i.e. entries into non-baited arms) and time to complete the task (s/arm) in the radial arm maze task. The first factor was the cannabinoid receptor antagonist rimonabant and the second factor was the cannabinoid receptor agonist (Δ9-THC or CP-55,950). The tail-flick data were expressed as percent maximal possible effect (%MPE), where %MPE = [(test - control) / (10 - control)] × 100. The rectal temperature data were expressed as post-injection temperature – pre-injection temperature. One-way ANOVAs were used to analyze dependent measures in the tetrad assay. The Tukey-Kramer post hoc test was used to analyze differences between treatment conditions. Differences were considered significant at the p < 0.05 level.
