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Chunk #49 — 7 Miscellaneous — CSNK1E

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Genetic factors modulating the response to stimulant drugs in humans.
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the gene, was associated with the response to amphetamine at 10 mg (but not 20 mg) as measured by the DEQ Feel Drug and ARCI Euphoria scales. Interestingly, other SNPs in CSNK1E have been associated with both heroin addiction in a case-control study (Levran et al. 2008) and ADHD in a family-based genome-wide association study (Mick et al. 2010), suggesting another possible link between ADHD, sensitivity to stimulants and drug abuse.