the literature were added to the JASPAR UNVALIDATED collection. We complemented the JASPAR CORE collection with 329 TF binding profiles and updated three existing profiles with new PFMs (Table 1 and Figure 1). We identified orthogonal support in the literature for 72 profiles previously stored in the JASPAR UNVALIDATED collection, promoting them to the CORE collection. Overall, the new JASPAR 2024 CORE collection represents a 20% increase in the number of profiles compared to the previous release (Supplementary Table S2). We augmented the JASPAR UNVALIDATED collection with 182 profiles (Supplementary Table S3). Finally, we updated the metadata associated with the profiles wherever possible (for 241 and 55 CORE and UNVALIDATED profiles, respectively) and removed 28 profiles (11 from the CORE collection and 17 from the UNVALIDATED collection) as these profiles were either redundant with other profiles, incorrectly supported by the literature, or associated with a protein not considered as a DNA-binding specific TF.
