paperKB
coga / coga-kb
Help
Sign in

Chunk #66 — Online Methods (Limit 3,000 words, at end of manuscript, currently 2,064) — Coexpression of SCZ genes throughout development

Source
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
Embedded
yes

Text

For each of the 67 SCZ-associated genes, we calculated average expression at each spatiotemporal point. We then calculated Z-Score of expression specificity using these values, and plotted Z-Scores to visually examine patterns of gene expression throughout development and across brain regions. Clusters were formally identified using a dendrogram cut at height 10 (Supplementary Figure 9).