We examined highly enriched categories that are most likely relevant in mediating the effects of the PPAR agonists. In order to emphasize the PPAR agonist-induced pathways and ontologies that might be regulating alcohol consumption, we chose a few genes from each enriched category, giving preference to those genes that have also been shown to be regulated by alcohol in the INIA IT-GED (http://inia.icmb.utexas.edu/).