On the session day, subjects arrived in the morning (9 am) and completed a urine toxicology screen, alcohol breathalyzer test, and urine pregnancy test; all individuals who participated in the study had negative findings. Subjects consumed a standardized 300 calorie breakfast and lunch to control for possible dietary effects on alcohol absorption, and completed within-session cumulative alcohol dosing (CAD) and a battery of subjective response instruments (see below). Breakfast was consumed two hrs. before the placebo drink, and lunch was consumed 45 min after the last alcohol drink (see below). Subjects were in a quiet laboratory room, and carefully monitored throughout the session. Following completion of the laboratory session, all subjects were admitted to the Johns Hopkins Clinical Research Unit for monitoring of any alcohol reactions. Subjects were discharged the following morning as approved by the study physician.
