confirming the completeness of the transcript. Furthermore, lncRNA submissions to INSDC are largely based on TSAs from short read datasets that may include artifactual exon combinations. RefSeq curators take a conservative approach to representing lncRNA genes, only manually creating RefSeqs (with a NR_ accession prefix) for high quality transcripts for which we have some certainty of the exon structure. Ideally, the transcript support should be spliced with at least three exons but two-exon and intronless transcripts can be represented if they are supported by promoter-associated epigenomics, poly(A) evidence, additional cDNAs, and/or RNA-Seq data. RefSeq lncRNA records for non-coding genes can be retrieved from NCBI's Nucleotide database using the search string ‘biomol ncrna lncrna[Properties]’ and selecting the RefSeq filter from the left column.
