The potential associations of the top 10 SNPs for both end points were then in a 2nd phase analysis studied for confirmation in an independent and well-defined cohort of HIV-1-infected individuals. The Genomics of Resistance to Immunodeficiency Virus cohort (GRIV) is a French case-control study in which either rapid progressors or non-progressors were compared with HIV-1-negative controls [18], [20].
