initial follow-up visit at age 7 years, six children were deceased and four others were recognized to have congenital malformations, and were thus excluded. Families were geographically stable in that they remained in the area but moved frequently within Detroit. The average number of home address changes was three. Of 656 eligible children at 7 years of age, 94% agreed to participate, and 85% completed lab testing (N=556; 49.1% female). Families and children participating at age 7 years were contacted again at age 14 for an additional follow-up study. The cohort size at age 14 was reduced to 530 by out-of-state moves (15 families), closed adoptions (2), child/teen deaths (3), and teen incarcerations (6). Twenty-six families (4.7% of the age 7 cohort) could not be located and 39 (7.0%) refused to participate. Completed teen assessments (N=432; 50.5 % female) represent 81.5% of the available age 7 cohort. Of these, retrospective reports about prior drinking in pregnancy were available for 288 mothers, 266 (92.4%) from the biological mothers themselves and an additional 22 retrospective assessments from kin collaborator reports. The final cohort of 288 represent 43.9% of the original recruitment cohort of 656, 51.8% of the 556 subjects completing initial testing
