MDD2000+ SNPs mapped to 18 454 genes. We list all genes with P<1 × 10−4 and all lie within linkage regions identified in the SLEP34 database of research findings for psychiatric disorders. Gene ontology annotations and names are provided for these genes (Table 4). Three are plausible candidate genes for MDD (GAL, ADCY3, PDK4) and others have a role in ion binding (ZDHHC19, ZNF83). None of the genes listed in Table 4 shows any evidence for association in the gene-based test applied to GAIN–MDD or the UK MDD GWAS results, although association at P<0.001 is retained for GAL in the gene-based test applied to the meta-analysis results.
