Correlations were obtained between ICV-normalized regional tissue volumes that were not age-corrected and age-corrected neurocognitive measures. In PSU, smaller pGM volume, although not significantly different from ALC and LD, related to worse visuospatial learning and memory (both r ≥0.50, p <0.05); no lobar WM volume in PSU correlated significantly with any of the neurocognitive measures. In ALC, worse visuospatial learning correlated with less total cortical GM and worse visuospatial skills with smaller fGM volume (both r = 0.39, p ≤0.014); lower fine motor skills related to smaller oGM volume (r = 0.43, p = 0.008). Also in ALC, lobar WM volume did not correlate significantly with neurocognitive measures, except intelligence, which correlated negatively with oWM (r = −0.36, p = 0.022). Finally, in the smaller group of LD, several correlations between neurocognitive measures and mostly occipital lobe volumes were observed, but these were all in the unexpected direction.
