It can be useful to divide the genome into blocks of variants which appear to be inherited together most of the time, since observed recombination patterns are substantially more “blocklike” than would be expected under a model of uniform recombination [21]. PLINK 1.0’s –blocks command implements a method of identifying these haplotype blocks by Gabriel et al. [22]. (More precisely, it is a restricted port of Haploview’s [23] implementation of the method).
