paperKB
coga / coga-kb
Help
Sign in

Chunk #12 — RESULTS — Phenotypic and functional characterization of pMGLs

Source
Efficient derivation of microglia-like cells from human pluripotent stem cells.
Embedded
yes

Text

Mature pMGLs stained positive for markers of murine and human microglia 10,11,29,30, with both TMEM119 and P2RY12 displaying a broad membrane and punctate vesicular expression pattern, consistently with their roles as part of the microglial sensome (Fig. 3e, f). The majority of pMGLs at this stage were positive for TMEM119, IBA1 and CD45 (Fig. 3g).