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Chunk #27 — PART 2: EXAMPLES OF THE QUESTIONS ADDRESSED WITH COGA DATA — Developmental effects

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The collaborative study on the genetics of alcoholism: Sample and clinical data.
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AUD is, by its very nature, a developmental disorder, which unfolds in a series of stages, from initiation, to regular use, to the development of problems, well argued in the literature to date. 36 , 37 , 38 Further, there is often a pattern of risk‐related behavior that precedes the onset of alcohol use. 39 , 40 Each of the stages of alcohol use is influenced by genetic factors, 38 , 41 , 42 , 43 as are the premorbid behaviors that comprise the spectrum of preaddiction risk. 44 , 45 , 46 , 47