Chunk #27 — RESULTS — Multivariate GWAS confirm a distinct genetic basis between alcohol consumption and misuse

Source

Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts.

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Lastly, gene-set analyses revealed that genes more closely linked to cellular responses to alcohol drinking (e.g., cellular response to retinoic acid) were associated with Consumption (Table S17), while the gene-sets related to postsynaptic modulation of chemical synaptic transmission were associated with Problems (Table S18).