Prior to ethanol administration, both genotypes demonstrated a similar degree of motor strength and remained on the wire for a comparable amount of time. (t(22) = −0.007, p = 0.995; Fig. 1B). However, after 2 g/kg ethanol, KO mice showed a marked decrease in the time spent on the wire compared to WT (genotype by time interaction, F(2,44) = 3.133, p = 0.05) but both genotypes recovered within a similar time frame.
