Chunk #23 — Results — GABRA2 variants, Impulsiveness and alcoholism

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Impulsiveness and insula activation during reward anticipation are associated with genetic variants in GABRA2 in a family sample enriched for alcoholism.

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The initial stimulus for this study was the well established association of Impulsiveness with AUD 47. Percentage of alcohol symptoms (N = 415; r2 = 0.128; p = 0.009) was significantly positively correlated with Impulsiveness (Spearman’s rho correlation). No gender differences were observed for Impulsiveness.