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Chunk #27 — 4. DISCUSSION

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DSM-5 cannabis use disorder: a phenotypic and genomic perspective.
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Upon examining gender and ethnic differences within classification version (e.g. DSM-5 diagnoses across males and females), the only significant variation was noted for DSM-5 diagnoses in AA women who were more likely to receive a diagnosis of DSM-5, but not DSM-IV cannabis use disorder, relative to their EA female counterparts. Intriguingly, also relative to their EA counterparts, they were less likely to endorse hazardous use but more likely to endorse numerous other criteria, with the exception of giving up important activities and use despite physical/psychological problems. This finding may be attributable to the larger number of AA women that were ascertained from the cocaine dependence study (46% AA versus 18.5% EA women are drawn from FSCD) versus other studies. Although this observation holds true for the men as well, and the prevalence (or mean number of symptoms endorsed) did not vary across AA and EA women, it is possible that AA women (but not men or EA women) from the FSCD study represent a high-risk group. For instance, when compared to the alcohol and nicotine dependence studies, AA women from