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Chunk #39 — DISCUSSION

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Gene expression changes in the ventral hippocampus and medial prefrontal cortex of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking.
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IPA comparison analysis of the 4 regions indicates that the vHip is the only region with decreases in the Wnt/B catenin, ILK signaling, synaptic long term potentiation and depression, corticotropin releasing hormone signaling, endothelin-1 signaling, and AMPK signaling (Table 3).