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Chunk #16 — 2. Methods — 2.5. Participants

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Cholinergic receptor gene (CHRM2) variation and familial loading for alcohol dependence predict childhood developmental trajectories of P300.
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Young adult subjects in the study gave written consent after the nature and purpose of the study was fully explained to them (consent forms approved by the University of Pittsburgh Institutional Review Board). Minor children provided assent with accompanying permission from parents.