Male mice, aged 7–8 weeks, from 23 inbred strains (Supplementary Table 5) were housed in Stanford University’s animal care facilities. Experimental protocols were approved by the Institutional Animal Care and Use Committee and complied with the Guide for the Care and Use of Laboratory Animals. Details are provided in Supplementary Methods. ANOVA was used to calculate a P value to assess the likelihood that the within-block genetic variation underlies the phenotypic distribution (i.e., the mean number of jumps) observed for the inbred strains examined. Haplotype data were examined for seven genes: CNIH3, CNIH2, GRIA1, GRIA2, CACNG8, GRIP1, and DLG4. P values were adjusted to control the false-discovery rate.38
