Figure 5 shows a plot of γ for each of the four regions, for the AD group and the control group as a function of the correlation threshold. In the left and the right hippocampus, the fitted growth curve was significantly lower (p<0.01) in the AD group, compared to the control group, reflecting lower clustering coefficient values for a range of threshold values from 0.1 to 0.6. A similar analysis in the left and right precentral gyrus, revealed no significant differences in the clustering coefficient values. Across the four regions, no significant differences in the clustering coefficient values were observed for correlation threshold values >0.6, mainly due to the large variance observed at higher threshold values. This analysis was extended to the remaining 86 regions of the whole brain functional network (see Table S1 to find regions that showed significant differences in clustering coefficient values between the two subject groups).
