2014); bipolar disorder (Andersson et al., 2008). In the present study, we find evidence of association among many variants within this DSE gene network and beta EEG, with the most robust associations (empirical p<0.05) observed for ZEB2, MCTP1, RND3, and CTBP2. Of these genes, ZEB2 and CTBP2 were also associated (empirical p-value>0.05) with DSM-V AUD (Table 3). Both ZEB2 and CTBP2 have been shown to influence gene expression in the brain, particularly during brain development, and have been previously correlated with traits of relevance to beta EEG and/or AUD.
