The same for-better-and-for-worse pattern of results are evident—and noted—in Brummett et al.'s27 investigation of more than 200 adults (mean age 58 years) who differed in whether or not they served as caregiver of a relative with Alzheimer's disease (see Figure 1) and in Eley et al.'s28 research on adolescent girls who were and were not exposed to risky family environments. Indeed, careful consideration of Figure 1 in Eley et al.'s28 report reveals a beneficial effect of the s/s genotype in low-stress environments, with females homozygous for short alleles being 25% less likely to be in the high depression group than l/l participants. This positive effect is actually greater than the negative one described by the authors in the case of the s/s genotype in a high stress environment (that is, 20% more likely to be in high depression group than l/l). Re-graphing Eley et al.'s28 Figure 1 using the format adopted originally by Caspi et al.5 brings this fact to the fore (see Figure 2 below). Comparison of the two figures highlights graphically the point being made repeatedly: the s/s
