Chunk #64 — II. Samples for genome studies of human addiction vulnerabilities and related phenotypes (Figure 2)

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Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects.

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J. Sample 10) Unrelated members of NHLBI twin pairs for assessment of frontal brain volume: 242 unrelated individuals were selected randomly from members of twin pairs from a population-based registry of European-American male World War II veteran twin pairs who received volumetric MRI studies as part of the National Heart, Lung, and Blood Institute (NHLBI) Twin Study. Studies were performed when subjects averaged 72.6 years of age and reported 13.6 years of education. Frontal lobar volumes, corrected for intracranial volumes, were obtained [117] in ways that produce inter-rater reliabilities > 0.90.