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Chunk #23 — Results — Genetic correlations — PTSD-alcohol consumption-related phenotypes

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Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes.
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The rGs using samples of AA individuals for PTSD phenotypes (i.e. PTSDf2, PTSD Re-Exp) and AUDIT-C were positive, and only that with PTSD Re-Exp was significant; although it did not pass FDR adjustment. Notably, this positive rG estimate in AA individuals, contrasts with the negative rGs estimates in EA samples for the same phenotypes. See online Supplementary Fig. S2 for boxplot with whiskers display of genetic correlations for those of EA and AA.