of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), and may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The KCNIP4 protein also interacts with presenilin. Gene is also found among top-findings from GWAS in schizophrenia (Sullivan et al. 2008) and shows P values at 10−5 in GWAS in bipolar disorder (Sklar et al. 2008)Also shows nominal association (P < 0.05) in quantitative GWAS by Lasky-Su et al. (2008b)rs65704260.7352.74E-056141239039IntergenicLies close to Schizophrenia linkage region (Lerer et al. 2003), with some evidence for nearby linkage region from a primary study in adult ADHD (Romanos et al. 2008) and the ADHD linkage meta-analysis (Zhou et al. 2008c)Also shows nominal association (P < 0.05) in quantitative GWAS by Lasky-Su et al. (2008b)rs15395490.73052.88E-051335349881Intron of DCLK1 = DCAMKL1Encodes doublecortin and CaM kinase-like 1, a microtubule-associated protein with microtubule polymerizing activity. Predominantly expressed in fetal and adult brainrs94844480.73852.94E-056141260753IntergenicLies close to schizophrenia linkage region (Lerer et al. 2003), with some evidence for nearby linkage region from a primary study in adult ADHD (Romanos et al. 2008) and the ADHD linkage meta-analysis (Zhou et al. 2008c)rs76576081.3562.96E-054168390756Intron of SPOCK3Encodes a member of a novel Ca(2+)-binding proteoglycan family, a component of the extracellular matrix, high expression
