To determine potentially separable effects of the alcohol prime on alcohol and water cues, we examined the effect of the alcohol prime on alcohol- and water-cue trials separately. We found an increase in activation to water cues following the prime (post- versus pre-priming contrast) across several cortical regions, including fronto-temporal regions and central opercular cortex. For alcohol cue trials, we found activation decreases in occipital regions (pre- versus post-priming) and increases in bilateral post-central and central opercular cortex (post- versus pre-priming; see supplementary materials).
